Protein name:
Insulin-like growth factor-binding protein 3 (IBP-3;IGF-binding protein 3;IGFBP-3) ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with XLKD1 (By similarity). Binds IGF2 more than IGF1. Forms a ternary complex of about 140 to 150 kDa with IGF1 or IGF2 and a 85 kDa glycoprotein (ALS). Interacts with HN.
Function:
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Subcellular Location:
Secreted
Protein Attributes:
50:
MQRARPTLWA | AALTLLVLLR | GPPVARAGAS | SAGLGPVVRC | EPCDARALAQ |
100:
CAPPPAVCAE | LVREPGCGCC | LTCALSEGQP | CGIYTERCGS | GLRCQPSPDE |
150:
ARPLQALLDG | RGLCVNASAV | SRLRAYLLPA | PPAPGNASES | EEDRSAGSVE |
200:
SPSVSSTHRV | SDPKFHPLHS | KIIIIKKGHA | KDSQRYKVDY | ESQSTDTQNF |
250:
SSESKRETEY | GPCRREMEDT | LNHLKFLNVL | SPRGVHIPNC | DKKGFYKKKQ |
291:
CRPSKGRKRG | FCWCVDKYGQ | PLPGYTTKGK | EDVHCYSMQS | K
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Bovine
Human
Mouse
Pig
ELISA Kit for Human IBP-3
ELISA Kit for Human IBP-3
ELISA Kit for Human IBP-3
ELISA Kit for Human IBP-3
ELISA Kit for Human IBP-3
Polyclonal Antibody for Human IBP-3
Polyclonal Antibody for Human IBP-3
Polyclonal Antibody for Human IBP-3
Polyclonal Antibody for Human IBP-3
Polyclonal Antibody for Human IBP-3
Monoclonal Antibody for Human IBP-3
Monoclonal Antibody for Human IBP-3
Monoclonal Antibody for Human IBP-3
Monoclonal Antibody for Human IBP-3
Monoclonal Antibody for Human IBP-3
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT GLY-32
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1);VARIANT GLY-32
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT GLY-32
tissue :
Skin .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 2);VARIANTS THR-56 AND SER-234
5.
"The DNA sequence of human chromosome 7."
Hillier L.W.
,
Fulton R.S.
,
Fulton L.A.
,
Graves T.A.
,
Pepin K.H.
,
Wagner-McPherson C.
,
Layman D.
,
Maas J.
,
Jaeger S.
,
Walker R.
,
Wylie K.
,
Sekhon M.
,
Becker M.C.
,
O'Laughlin M.D.
,
Schaller M.E.
,
Fewell G.A.
,
Delehaunty K.D.
,
Miner T.L.
,
Nash W.E.
,
Cordes M.
,
Du H.
,
Sun H.
,
Edwards J.
,
Bradshaw-Cordum H.
,
Ali J.
,
Andrews S.
,
Isak A.
,
Vanbrunt A.
,
Nguyen C.
,
Du F.
,
Lamar B.
,
Courtney L.
,
Kalicki J.
,
Ozersky P.
,
Bielicki L.
,
Scott K.
,
Holmes A.
,
Harkins R.
,
Harris A.
,
Strong C.M.
,
Hou S.
,
Tomlinson C.
,
Dauphin-Kohlberg S.
,
Kozlowicz-Reilly A.
,
Leonard S.
,
Rohlfing T.
,
Rock S.M.
,
Tin-Wollam A.-M.
,
Abbott A.
,
Minx P.
,
Maupin R.
,
Strowmatt C.
,
Latreille P.
,
Miller N.
,
Johnson D.
,
Murray J.
,
Woessner J.P.
,
Wendl M.C.
,
Yang S.-P.
,
Schultz B.R.
,
Wallis J.W.
,
Spieth J.
,
Bieri T.A.
,
Nelson J.O.
,
Berkowicz N.
,
Wohldmann P.E.
,
Cook L.L.
,
Hickenbotham M.T.
,
Eldred J.
,
Williams D.
,
Bedell J.A.
,
Mardis E.R.
,
Clifton S.W.
,
Chissoe S.L.
,
Marra M.A.
,
Raymond C.
,
Haugen E.
,
Gillett W.
,
Zhou Y.
,
James R.
,
Phelps K.
,
Iadanoto S.
,
Bubb K.
,
Simms E.
,
Levy R.
,
Clendenning J.
,
Kaul R.
,
Kent W.J.
,
Furey T.S.
,
Baertsch R.A.
,
Brent M.R.
,
Keibler E.
,
Flicek P.
,
Bork P.
,
Suyama M.
,
Bailey J.A.
,
Portnoy M.E.
,
Torrents D.
,
Chinwalla A.T.
,
Gish W.R.
,
Eddy S.R.
,
McPherson J.D.
,
Olson M.V.
,
Eichler E.E.
,
Green E.D.
,
Waterston R.H.
,
Wilson R.K.
more...
Nature424:157-164(2003)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.
"Human chromosome 7: DNA sequence and biology."
Scherer S.W.
,
Cheung J.
,
MacDonald J.R.
,
Osborne L.R.
,
Nakabayashi K.
,
Herbrick J.-A.
,
Carson A.R.
,
Parker-Katiraee L.
,
Skaug J.
,
Khaja R.
,
Zhang J.
,
Hudek A.K.
,
Li M.
,
Haddad M.
,
Duggan G.E.
,
Fernandez B.A.
,
Kanematsu E.
,
Gentles S.
,
Christopoulos C.C.
,
Choufani S.
,
Kwasnicka D.
,
Zheng X.H.
,
Lai Z.
,
Nusskern D.R.
,
Zhang Q.
,
Gu Z.
,
Lu F.
,
Zeesman S.
,
Nowaczyk M.J.
,
Teshima I.
,
Chitayat D.
,
Shuman C.
,
Weksberg R.
,
Zackai E.H.
,
Grebe T.A.
,
Cox S.R.
,
Kirkpatrick S.J.
,
Rahman N.
,
Friedman J.M.
,
Heng H.H.Q.
,
Pelicci P.G.
,
Lo-Coco F.
,
Belloni E.
,
Shaffer L.G.
,
Pober B.
,
Morton C.C.
,
Gusella J.F.
,
Bruns G.A.P.
,
Korf B.R.
,
Quade B.J.
,
Ligon A.H.
,
Ferguson H.
,
Higgins A.W.
,
Leach N.T.
,
Herrick S.R.
,
Lemyre E.
,
Farra C.G.
,
Kim H.-G.
,
Summers A.M.
,
Gripp K.W.
,
Roberts W.
,
Szatmari P.
,
Winsor E.J.T.
,
Grzeschik K.-H.
,
Teebi A.
,
Minassian B.A.
,
Kere J.
,
Armengol L.
,
Pujana M.A.
,
Estivill X.
,
Wilson M.D.
,
Koop B.F.
,
Tosi S.
,
Moore G.E.
,
Boright A.P.
,
Zlotorynski E.
,
Kerem B.
,
Kroisel P.M.
,
Petek E.
,
Oscier D.G.
,
Mould S.J.
,
Doehner H.
,
Doehner K.
,
Rommens J.M.
,
Vincent J.B.
,
Venter J.C.
,
Li P.W.
,
Mural R.J.
,
Adams M.D.
,
Tsui L.-C.
more...
Science300:767-772(2003)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.
Mural R.J.
,
Istrail S.
,
Sutton G.G.
,
Florea L.
,
Halpern A.L.
,
Mobarry C.M.
,
Lippert R.
,
Walenz B.
,
Shatkay H.
,
Dew I.
,
Miller J.R.
,
Flanigan M.J.
,
Edwards N.J.
,
Bolanos R.
,
Fasulo D.
,
Halldorsson B.V.
,
Hannenhalli S.
,
Turner R.
,
Yooseph S.
,
Lu F.
,
Nusskern D.R.
,
Shue B.C.
,
Zheng X.H.
,
Zhong F.
,
Delcher A.L.
,
Huson D.H.
,
Kravitz S.A.
,
Mouchard L.
,
Reinert K.
,
Remington K.A.
,
Clark A.G.
,
Waterman M.S.
,
Eichler E.E.
,
Adams M.D.
,
Hunkapiller M.W.
,
Myers E.W.
,
Venter J.C.
more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Kidney .
tissue :
Spleen .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 28-65
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 28-45;INTERACTION WITH IGF2;VARIANT GLY-32
tissue :
Cerebrospinal fluid .
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 28-42
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH HN
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-136
tissue :
Plasma .
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-136 AND ASN-199
tissue :
Plasma .
15.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-136
tissue :
Liver .
16.
"A strategy for precise and large scale identification of core fucosylated glycoproteins."
Jia W.
,
Lu Z.
,
Fu Y.
,
Wang H.P.
,
Wang L.H.
,
Chi H.
,
Yuan Z.F.
,
Zheng Z.B.
,
Song L.N.
,
Han H.H.
,
Liang Y.M.
,
Wang J.L.
,
Cai Y.
,
Zhang Y.K.
,
Deng Y.L.
,
Ying W.T.
,
He S.M.
,
Qian X.H.
Mol. Cell. Proteomics8:913-923(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION AT ASN-116; ASN-136 AND ASN-199
17.
"Identification of a novel cell death receptor mediating IGFBP-3-induced anti-tumor effects in breast and prostate cancer."
Ingermann A.R.
,
Yang Y.F.
,
Han J.
,
Mikami A.
,
Garza A.E.
,
Mohanraj L.
,
Fan L.
,
Idowu M.
,
Ware J.L.
,
Kim H.S.
,
Lee D.Y.
,
Oh Y.
J. Biol. Chem.285:30233-30246(2010)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH TMEM219
18.
"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T.
,
Jones S.
,
Wood L.D.
,
Parsons D.W.
,
Lin J.
,
Barber T.D.
,
Mandelker D.
,
Leary R.J.
,
Ptak J.
,
Silliman N.
,
Szabo S.
,
Buckhaults P.
,
Farrell C.
,
Meeh P.
,
Markowitz S.D.
,
Willis J.
,
Dawson D.
,
Willson J.K.V.
,
Gazdar A.F.
,
Hartigan J.
,
Wu L.
,
Liu C.
,
Parmigiani G.
,
Park B.H.
,
Bachman K.E.
,
Papadopoulos N.
,
Vogelstein B.
,
Kinzler K.W.
,
Velculescu V.E.
more...
Science314:268-274(2006)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANTS [LARGE SCALE ANALYSIS] MET-7 AND CYS-252